Tobrex

DRUG DESCRIPTION

TOBREX® (tobramycin ophthalmic ointment) 0.3% is a sterile topical ophthalmic antibiotic formulation prepared specifically for topical therapy of external ophthalmic infections.

Each gram of TOBREX (tobramycin ophthalmic ointment) 0.3% contains: Active: tobramycin 0.3% (3 mg). Preservative: chlorobutanol 0.5%. Inactives: mineral oil, white petrolatum.

Tobramycin is a water-soluble aminoglycoside antibiotic active against a wide variety of gram-negative and gram-positive ophthalmic pathogens.

The chemical structure of tobramycin is:

TOBREX (tobramycin) Structural Formula Illustration

Molecular formula: C18H37N5O9

Molecular weight: 467.52

Chemical name: 0-{3-amino-3-deoxy-?-D-gluco-pyranosyl-(1#4) }-0-{2,6-diamino-2,3,6-trideoxy-?-D-ribohexo-pyranosyl-(1#6) }-2-deoxystreptamine.

What are the possible side effects of tobramycin ophthalmic (Aktob, Tobralcon, Tobrasol, Tobrex)?

Serious side effects are not expected with this medication.

Commonly, some eye burning, stinging, irritation, itching, redness, blurred vision, eyelid itching, eyelid swelling, or sensitivity to light may occur.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...

Read All Potential Side Effects and See Pictures of Tobrex »

What are the precautions when taking tobramycin ophthalmic ointment (Tobrex)?

Before using tobramycin, tell your doctor or pharmacist if you are allergic to it; or to other aminoglycosides (e.g., gentamicin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: other eye problems.

This drug may cause temporary blurred or unstable vision after you apply it. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

It is...

Read All Potential Precautions of Tobrex »


Tobrex Consumer (continued)

SIDE EFFECTS: Temporary blurred vision, tearing, eye redness, eye discomfort, or eyelid itching/swelling may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Use of this medication for prolonged or repeated periods may result in a new fungal eye infection. Do not use it for longer than prescribed. Contact your doctor if you notice new or worsening symptoms.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using tobramycin, tell your doctor or pharmacist if you are allergic to it; or to other aminoglycosides (e.g., gentamicin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: other eye problems.

This drug may cause temporary blurred or unstable vision after you apply it. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding.


Tobrex Patient Information Including Side Effects

Brand Names: Aktob, Tobralcon, Tobrasol, Tobrex

Generic Name: tobramycin ophthalmic (Pronunciation: TOE bra MYE sin off THAL mik)

  • What is tobramycin ophthalmic (Tobrex)?
  • What are the possible side effects of tobramycin ophthalmic (Tobrex)?
  • What is the most important information I should know about tobramycin ophthalmic (Tobrex)?
  • What should I discuss with my healthcare provider before using tobramycin ophthalmic (Tobrex)?
  • How should I use tobramycin ophthalmic (Tobrex)?
  • What happens if I miss a dose (Tobrex)?
  • What happens if I overdose (Tobrex)?
  • What should I avoid while using tobramycin ophthalmic (Tobrex)?
  • What other drugs will affect tobramycin ophthalmic (Tobrex)?
  • Where can I get more information?

What is tobramycin ophthalmic (Tobrex)?

Tobramycin ophthalmic is an antibiotic.

Tobramycin ophthalmic is used to treat bacterial infections of the eyes.

Tobramycin ophthalmic may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of tobramycin ophthalmic (Tobrex)?

Serious side effects are not expected with this medication.

Commonly, some eye burning, stinging, irritation, itching, redness, blurred vision, eyelid itching, eyelid swelling, or sensitivity to light may occur.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about tobramycin ophthalmic (Tobrex)?

Do not touch the dropper or tube opening to any surface, including your eyes or hands. The dropper or tube opening is sterile. If it becomes contaminated, it could cause an infection in the eye.

Apply light pressure to the inside corner of your eye (near your nose) after each drop to prevent the fluid from draining down the tear ducts.

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