Timoptic in Ocudose

DRUG DESCRIPTION

Timolol maleate is a non-selective beta-adrenergic receptor blocking agent. Its chemical name is (-)-l-(tert-butylamino)-3-[(4-morpholino-l,2,5-thiadiazol-3-yl)oxy]-2-propanolmaleate (1:1) (salt). Timolol maleate possesses an asymmetric carbon atom in its structure and is provided as the levo-isomer. The optical rotation of timolol maleate is:

25
[?] in l.0N HC1 (C = 5%) = -12.2 (-11.7 to -12.5).
405 nm

Its molecular formula is C13H24N4O3SC4H4O4 and its structural formula is:

Timoptic (Timolol Maleate) Structural Formula Illustration

Timolol maleate has a molecular weight of 432.50. It is a white, odorless, crystalline powder which is soluble in water, methanol, and alcohol. Timolol maleate is stable at room temperature.

Timolol maleate ophthalmic solution is supplied in two formulations: Ophthalmic Solution TIMOPTIC. (timolol maleate ophthalmic solution), which contains the preservative benzalkonium chloride; and Ophthalmic Solution TIMOPTIC (timolol maleate ophthalmic solution), the preservative-free formulation.

Preservative-free Ophthalmic Solution TIMOPTIC is supplied in OCUDOSE, a unit dose container, as a sterile, isotonic, buffered, aqueous solution of timolol maleate in two dosage strengths: Each mL of Preservative-free TIMOPTIC in OCUDOSE 0.25% contains 2.5 mg of timolol (3.4 mg of timolol maleate). The pH of the solution is approximately 7.0, and the osmolarity is 252-328 mOsm. Each mL of Preservative-free TIMOPTIC in OCUDOSE 0.5% contains 5 mg of timolol (6.8 mg of timolol maleate). Inactive ingredients: monobasic and dibasic sodium phosphate, sodium hydroxide to adjust pH, and water for injection.

What are the possible side effects of timolol ophthalmic?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • swelling or redness of your eyelids;
  • eye redness, discomfort, or sensitivity to light;
  • drainage, crusting, or oozing of your eyes or eyelids;
  • depressed mood, confusion, hallucinations, unusual thoughts or behavior;
  • wheezing,...

Read All Potential Side Effects and See Pictures of Timoptic in Ocudose


Timoptic in Ocudose Patient Information Including Side Effects

Brand Names: Betimol, Istalol, Timoptic Ocudose, Timoptic Ocumeter, Timoptic Ocumeter Plus, Timoptic-XE

Generic Name: timolol ophthalmic (Pronunciation: TIM oh lol off THAL mik)

  • What is timolol ophthalmic (Timoptic in Ocudose)?
  • What are the possible side effects of timolol ophthalmic?
  • What is the most important information I should know about timolol ophthalmic?
  • What should I discuss with my healthcare provider before using timolol ophthalmic?
  • How should I use timolol ophthalmic?
  • What happens if I miss a dose?
  • What happens if I overdose?
  • What should I avoid while using timolol ophthalmic?
  • What other drugs will affect timolol ophthalmic?
  • Where can I get more information?

What is timolol ophthalmic (Timoptic in Ocudose)?

Timolol is a beta-blocker that also reduces pressure inside the eye.

Timolol ophthalmic (for the eyes) is used to treat open-angle glaucoma and other causes of high pressure inside the eye.

Timolol ophthalmic may also be used for other purposes not listed in this medication guide.

What are the possible side effects of timolol ophthalmic?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • swelling or redness of your eyelids;
  • eye redness, discomfort, or sensitivity to light;
  • drainage, crusting, or oozing of your eyes or eyelids;
  • depressed mood, confusion, hallucinations, unusual thoughts or behavior;
  • wheezing, gasping, or other breathing problems;
  • swelling, rapid weight gain;
  • chest pain, slow or uneven heart rate; or
  • feeling short of breath, even with mild exertion.

Less serious side effects may include:

  • blurred vision, double vision, drooping eyelid;
  • burning or stinging in your eye;
  • headache, weakness, drowsiness;
  • numbness, tingling, or cold feeling in your hands or feet;
  • ringing in your ears;
  • dry mouth;
  • nausea, diarrhea, loss of appetite, upset stomach;
  • skin rash or worsening psoriasis;
  • sleep problems (insomnia); or
  • cough, stuffy nose.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about timolol ophthalmic?

Do not allow the dropper to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not use any other eye medication unless your doctor has prescribed it for you. If you use another eye medication, use it at least 10 minutes before or after using timolol ophthalmic. Do not use the medications at the same time.

Timolol ophthalmic can cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.

Related Drug Centers
  • Timoptic-XE
  • Timoptic
  • Timoptic in Ocudose
  • Istalol
  • Betimol


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