Trivaris

DRUG DESCRIPTION

TRIVARIS™ (triamcinolone acetonide injectable suspension) 80 mg/mL is a synthetic glucocorticoid corticosteroid with anti-inflammatory action. This formulation is suitable for intravitreal, intra-muscular, and intra-articular use. This formulation is not for intravenous injection. Each syringe of the sterile aqueous gel suspension contains 8 mg triamcinolone acetonide in 0.1 mL (8% suspension) in a vehicle containing w/w percents of 2.3% sodium hyaluronate; 0.63% sodium chloride; 0.3% sodium phosphate, dibasic; 0.04% sodium phosphate, monobasic; and water for injection. TRIVARIS (triamcinolone acetonide injectable suspension) ™ is preservativefree with a pH of 7.0 to 7.4. The chemical name for triamcinolone acetonide is 9??­fluoro-11?,16?,17,21-tetrahydroxypregna?­1,4-diene-3,20-dione cyclic 16,17-acetal with acetone.

Its structural formula is:

TRIVARIS™ (triamcinolone acetonide injectable suspension) Tablets Structural Formula Illustration

MW 434.50 with a molecular formula of C24H31FO6. Triamcinolone acetonide occurs as a white to cream-colored crystalline powder having not more than a slight odor, and is practically insoluble in water and very soluble in alcohol.

What are the possible side effects of triamcinolone injection?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • fast, slow, or uneven heart rate;
  • feeling short of breath, even with mild exertion;
  • swelling, rapid weight gain;
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);
  • problems with your...

Read All Potential Side Effects and See Pictures of Trivaris »


Trivaris Patient Information Including Side Effects

Brand Names: Aristospan Injection, Clinacort, Clinalog, Kenalog-10, Kenalog-40, Ken-Jec 40, TAC 3, Triamonide 40, U-Tri-Lone

Generic Name: triamcinolone (injection) (Pronunciation: trye am SIN oh lone)

  • What is triamcinolone injection (Trivaris)?
  • What are the possible side effects of triamcinolone injection?
  • What is the most important information I should know about triamcinolone injection?
  • What should I discuss with my health care provider before receiving triamcinolone injection?
  • How is triamcinolone injection given?
  • What happens if I miss a dose?
  • What happens if I overdose?
  • What should I avoid while receiving triamcinolone injection?
  • What other drugs will affect triamcinolone injection?
  • Where can I get more information?

What is triamcinolone injection (Trivaris)?

Triamcinolone injection is a steroid. It prevents the release of substances in the body that cause inflammation.

Triamcinolone injection is injected into the joint space to treat inflammation of the joints or tendons to treat arthritis, bursitis, or epicondylitis (tennis elbow). It is usually given in these conditions only as a short-term treatment of a severe or aggravated episode.

Triamcinolone injection is injected into soft tissues of the body to treat certain skin disorders caused by autoimmune conditions such as lupus, psoriasis, lichen planus, and others.

Triamcinolone injection may also be used for other purposes not listed in this medication guide.

What are the possible side effects of triamcinolone injection?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • fast, slow, or uneven heart rate;
  • feeling short of breath, even with mild exertion;
  • swelling, rapid weight gain;
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);
  • problems with your vision;
  • eye swelling, redness, discomfort, or drainage (may be signs of infection);
  • severe depression, changes in mood or behavior;
  • seizure (convulsions); or
  • muscle pain, tenderness, or weakness.

Less serious side effects may include:

  • nausea, bloating, appetite changes;
  • stomach or side pain;
  • headache, sleep problems (insomnia);
  • acne, scaling, or other skin changes;
  • a wound that is slow to heal;
  • thinning hair;
  • bruising or swelling;
  • sweating more than usual; or
  • irregular menstrual periods.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about triamcinolone injection?

You should not receive this medication if you are allergic to triamcinolone, or if you have a condition called idiopathic thrombocytopenic purpura (ITP):

Before receiving triamcinolone injection, tell your doctor if you are allergic to any drugs, or if you have any type of infection (including tuberculosis), a thyroid disorder, a muscle disorder, stomach or intestinal problems, or if you have recently had a heart attack.

Long-term use of steroids can also cause harmful effects on your eyes. Your doctor may want you to have regular eye exams while you are receiving triamcinolone injection.

Steroids can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.

Steroids can lower the blood cells that help your body fight infections, making it easier for you to get sick from being around others who are ill, or from bacteria in a skin wound. Use caution to prevent illness, infection, or injury.

Do not receive a "live" vaccine while you are being treated with triamcinolone injection. The live vaccine may not work as well during this time, and may not fully protect you from disease.

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroids.

There are many other medicines that can cause serious medical problems if you take them together with triamcinolone injection. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

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