Actisite

(Generic versions may still be available.)

DRUG DESCRIPTION

ActisiteŽ (tetracycline periodontal) periodontal fiber for periodontal pocket placement consists of a 23 cm (9 inch) monofilament of ethylene/vinyl acetate copolymer, 0.5 mm in diameter, containing 12.7 mg of evenly dispersed tetracycline hydrochloride, USP.ActisiteŽ (tetracycline periodontal) fiber provides continuous release of tetracycline for 10 days.

Actisite (tetracycline periodontal) is an antibiotic originally isolated from Streptomyces aureofaciens. Chemically it is the monohydrochloride of [4S-(4 ?,4a ?,5a ?, 6 ?, 12a ?)] -4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12, 12a-pentahydroxy-6-methyl-1,11-dioxo-2- naphthacenecarboxamide.

Empirical Formula: C22H24N2O8.HCl.

The chemical structure of tetracycline hydrochloride:



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