The active component of QVAR (beclomethasone dipropionate hfa) 40 mcg Inhalation Aerosol and QVAR 80 mcg Inhalation Aerosol is beclomethasone dipropionate, USP, an anti-inflammatory corticosteroid having the chemical name 9-chloro-11?,17,21-trihydroxy-16??­methylpregna-1,4-diene-3, 20-dione 17,21-dipropionate. Beclomethasone dipropionate (BDP) is a diester of beclomethasone, a synthetic corticosteroid chemically related to dexamethasone. Beclomethasone differs from dexamethasone in having a chlorine at the 9-alpha carbon in place of a fluorine, and in having a 16 beta-methyl group instead of a 16 alpha-methyl group. Beclomethasone dipropionate is a white to creamy white, odorless powder with a molecular formula of C28H37ClO7 and a molecular weight of 521.1. Its chemical structure is:

Flunisolide hemihydrate, the active component of AEROSPAN™ (flunisolide HFA, 80 mcg) Inhalation Aerosol, is a corticosteroid having the chemical name 6?-Fluoro-11?, 16?, 17, 21 –tetrahydroxylpregna-1, 4-diene-3, 20-dione cyclic-16, 17-acetal with acetone, hemihydrate and the following chemical structure:

The active component of PROVENTIL® HFA (albuterol sulfate) Inhalation Aerosol is albuterol sulfate, USP racemic ?1 [(tert-Butylamino)methyl]-4-hydroxy-m-xylene-?,?'-diol sulfate (2:1)(salt), a relatively selective beta2-adrenergic bronchodilator having the following chemical structure:

The active component of FLOVENT HFA 44 mcg Inhalation Aerosol, FLOVENT HFA 110 mcg Inhalation Aerosol, and FLOVENT HFA 220 mcg Inhalation Aerosol is fluticasone propionate, a corticosteroid having the chemical name S-(fluoromethyl) 6?,9-difluoro-11?,17 dihydroxy-16?-methyl-3-oxoandrosta-1,4-diene-17?-carbothioate, 17-propionate and the following chemical structure:

The active ingredient in ATROVENT HFA is ipratropium bromide (as the monohydrate). It is an anticholinergic bronchodilator chemically described as 8azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-,bromide monohydrate, (3-endo, 8-syn)-: a synthetic quaternary ammonium compound, chemically related to atropine. The structural formula for ipratropium bromide is:

The active component of VENTOLIN HFA is albuterol sulfate, USP, the racemic form of albuterol and a relatively selective beta2-adrenergic bronchodilator. Albuterol sulfate has the chemical name ?1-[(tert-butylamino)methyl]-4-hydroxy-m-xylene-?, ?' -diol sulfate (2:1)(salt) and the following chemical structure:

The active ingredient of PROAIR HFA (albuterol sulfate) Inhalation Aerosol is albuterol sulfate, a racemic salt, of albuterol. Albuterol sulfate has the chemical name ?1-[(tertbutylamino) methyl]-4-hydroxy-m-xylene-?,?'-diol sulfate (2:1) (salt), and has the following chemical structure:

The active component of XOPENEX HFA (levalbuterol tartrate) Inhalation Aerosol is levalbuterol tartrate, the (R)-enantiomer of albuterol. Levalbuterol tartrate is a relatively selective beta2-adrenergic receptor agonist (see CLINICAL PHARMACOLOGY). Levalbuterol tartrate has the chemical name (R)-?1-[[(1,1-dimethylethyl)amino]methyl]- 4-hydroxy-1,3-benzenedimethanol L-tartrate (2:1 salt), and it has the following chemical structure:

ADVAIR HFA (fluticasone propionate and salmeterol) 45/21 Inhalation Aerosol, ADVAIR HFA (fluticasone propionate and salmeterol) 115/21 Inhalation Aerosol, and ADVAIR HFA (fluticasone propionate and salmeterol) 230/21 Inhalation Aerosol are combinations of fluticasone propionate and salmeterol xinafoate.