KALETRA (lopinavir/ritonavir) is a co-formulation of lopinavir and ritonavir. Lopinavir is an inhibitor of the HIV protease. As co-formulated in KALETRA, ritonavir inhibits the CYP3A?­mediated metabolism of lopinavir, thereby providing increased plasma levels of lopinavir.

KALETRA (lopinavir/ritonavir) is a co-formulation of lopinavir and ritonavir. Lopinavir is an inhibitor of the HIV-1 protease. As co-formulated in KALETRA (lopinavir, ritonavir tablets) , ritonavir inhibits the CYPSA-mediated metabolism of lopinavir, thereby providing increased plasma levels of lopinavir.