MYOZYME® (alglucosidase alfa) consists of the human enzyme acid ?-glucosidase (GAA), encoded by the most predominant of nine observed haplotypes of this gene. MYOZYME (alglucosidase alfa) is produced by recombinant DNA technology in a Chinese hamster ovary cell line. Alglucosidase alfa degrades glycogen by catalyzing the hydrolysis of ?-1,4- and ?-1,6-glycosidic linkages of lysosomal glycogen.