Vascor

(Generic versions may still be available.)

DRUG DESCRIPTION

VASCOR (bepridil hydrochloride) is a calcium channel blocker that has well characterized anti-anginal properties and known but poorly characterized type 1 anti-arrhythmic and anti-hypertensive properties. It has inhibitory effects on both the slow calcium and fast sodium inward currents in myocardial and vascular smooth muscle, interferes with calcium binding to calmodulin, and blocks both voltage and receptor operated calcium channels. It is not related chemically to other calcium channel blockers such as diltiazem hydrochloride, nifedipine and verapamil hydrochloride.

Bepridil hydrochloride monohydrate is a white to off-white, crystalline powder with a bitter taste. It is slightly soluble in water, very soluble in ethanol, methanol and chloroform, and freely soluble in acetone. The molecular weight of bepridil hydrochloride monohydrate is 421.02. Its molecular formula is C 24 H 34 N 2 O??HCl??H 2 O.

()-(beta)-[(2-Methylpropoxy)methyl]-N-phenyl- N -(phenyl- methyl)-1-pyrrolidineethanamine monohydrochloride monohydrate

VASCOR (bepridil) is available as film-coated tablets for oral use containing 200, 300, or 400 mg of bepridil hydrochloride monohydrate. Inactive ingredients: hydroxypropyl methylcellulose, lactose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, silicon dioxide, pregelatinized corn starch, corn starch, titanium dioxide, FD&C Blue #1.

What are the possible side effects of bepridil (Vascor)?

If you experience any of the following serious side effects, stop taking bepridil and call your doctor immediately or seek emergency medical treatment:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
  • unusually fast or slow heartbeat;
  • fainting or severe dizziness;
  • chest pain;
  • abnormal behavior or psychosis;
  • yellowing of your skin or eyes (jaundice); or
  • swelling of your legs or...

Read All Potential Side Effects and See Pictures of Vascor


Vascor Patient Information Including Side Effects

Brand Names: Vascor

Generic Name: bepridil (Pronunciation: BE pri dil)

  • What is bepridil (Vascor)?
  • What are the possible side effects of bepridil (Vascor)?
  • What is the most important information I should know about bepridil (Vascor)?
  • What should I discuss with my healthcare provider before taking bepridil (Vascor)?
  • How should I take bepridil (Vascor)?
  • What happens if I miss a dose (Vascor)?
  • What happens if I overdose (Vascor)?
  • What should I avoid while taking bepridil (Vascor)?
  • What other drugs will affect bepridil (Vascor)?
  • Where can I get more information?

What is bepridil (Vascor)?

Bepridil is in a class of drugs called calcium channel blockers. Bepridil relaxes (widens) your blood vessels (veins and arteries), which makes it easier for your heart to pump and reduces its workload.

Bepridil is used to treat hypertension (high blood pressure) and to treat angina (chest pain).

Bepridil may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of bepridil (Vascor)?

If you experience any of the following serious side effects, stop taking bepridil and call your doctor immediately or seek emergency medical treatment:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
  • unusually fast or slow heartbeat;
  • fainting or severe dizziness;
  • chest pain;
  • abnormal behavior or psychosis;
  • yellowing of your skin or eyes (jaundice); or
  • swelling of your legs or ankles.

Other, less serious side effects may be more likely to occur. Continue to take bepridil and talk to your doctor if you experience

  • unusual fatigue or tiredness;
  • nausea, upset stomach, diarrhea, or constipation;
  • headache;
  • nervousness or mild dizziness;
  • insomnia; or
  • tremor (shaking).

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What is the most important information I should know about bepridil (Vascor)?

Do not stop taking this medication unless your doctor approves. If you stop taking your medication, your condition could become much worse.

Follow any diet or exercise recommendations for your condition.

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