Zyclara

DRUG DESCRIPTION

ZYCLARA (imiquimod) Cream, 2.5% or 3.75% is intended for topical administration. Each gram contains 25 mg or 37.5 mg of imiquimod, respectively, in a white to faintly yellow oilin-water cream base consisting of isostearic acid, cetyl alcohol, stearyl alcohol, white petrolatum, polysorbate 60, sorbitan monostearate, glycerin, xanthan gum, purified water, benzyl alcohol, methylparaben, and propylparaben.

Chemically, imiquimod is 1-(2-methylpropyl)-1H-imidazol[4,5-c]quinolin-4-amine. Imiquimod has a molecular formula of C14H16N4 and a molecular weight of 240.3. Its structural formula is:

ZOSYNŽ ZYCLARA (imiquimod) Structural Formula Illustration

ZYCLARA (imiquimod) Cream, 2.5% and 3.75% come as premeasured packets containing 6.25 mg and 9.4 mg of imiquimod, respectively, in 0.25 g of cream. ZYCLARA (imiquimod) Cream, 3.75% also comes in pumps which dispense 8.8 mg of imiquimod in 0.235 g of cream per full actuation of the pump after priming. ZYCLARA (imiquimod) Cream, 3.75% pumps should be primed before initial use by repeatedly depressing the actuator until cream is dispensed. It is not necessary to repeat this priming process during treatment.



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